Effect of Phosphatidylcholine and Cholesterol on pH-Sensitive Liposomes.
نویسندگان
چکیده
منابع مشابه
Preparation and properties evaluation of a novel pH-sensitive liposomes based on imidazole-modified cholesterol derivatives.
As a new kind of drug carries, pH-sensitive liposomes have been widely studied in tumor therapy for their advantages of target ability and sustained-release. Here, we synthesized a pH-sensitive material, N-(3-Aminopropyl)imidazole-cholesterol (IM-Chol) and prepared a novel pH-sensitive liposomes using IM-Chol and phosphatidylcholine. IM-Chol was synthesized through amidation reaction between th...
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چکیده ندارد.
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Cholesterol Organization in Phosphatidylcholine Liposomes: A Surface Plasmon Resonance Study
Models for the organization of sterols into regular arrays within phospholipid bilayers have been proposed previously. The existence of such arrays in real systems has been supported by the fact that concentration-dependent sterol properties show discontinuities at the cholesterol mole fractions corresponding to regular lattice arrangements. Experimental results presented here are based on a su...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1993
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.41.1003